A cognitive task analysis of a visual analytic workflow: Exploring molecular interaction networks in systems biology

نویسندگان

  • Barbara Mirel
  • Felix Eichinger
  • Benjamin J Keller
  • Matthias Kretzler
چکیده

BACKGROUND Bioinformatics visualization tools are often not robust enough to support biomedical specialists’ complex exploratory analyses. Tools need to accommodate the workflows that scientists actually perform for specific translational research questions. To understand and model one of these workflows, we conducted a case-based, cognitive task analysis of a biomedical specialist’s exploratory workflow for the question: What functional interactions among gene products of high throughput expression data suggest previously unknown mechanisms of a disease? RESULTS From our cognitive task analysis four complementary representations of the targeted workflow were developed. They include: usage scenarios, flow diagrams, a cognitive task taxonomy, and a mapping between cognitive tasks and user-centered visualization requirements. The representations capture the flows of cognitive tasks that led a biomedical specialist to inferences critical to hypothesizing. We created representations at levels of detail that could strategically guide visualization development, and we confirmed this by making a trial prototype based on user requirements for a small portion of the workflow. CONCLUSIONS Our results imply that visualizations should make available to scientific users “bundles of features” consonant with the compositional cognitive tasks purposefully enacted at specific points in the workflow. We also highlight certain aspects of visualizations that: (a) need more built-in flexibility; (b) are critical for negotiating meaning; and (c) are necessary for essential metacognitive support.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Exploring Language Learners’ Cognitive Processes in On-line ESP Courses via Think-aloud Protocol Analysis

The present study aims to investigate language learners’ cognitive processes in on-line ESP courses. Three modes of inquiry are used: think-aloud protocol analysis, screen capture analysis, and correlation analysis. The theoretical foundations for the evaluation of the cognitive aspect of Ferdowsi Univeristy of Mashhad E-learning System are drawn from cognitive load theory, cognitive apprentice...

متن کامل

Analysis of users’ query reformulation behavior in Web with regard to Wholis-tic/analytic cognitive styles, Web experience, and search task type

Background and Aim: The basic aim of the present study is to investigate users’ query reformulation behavior with regard to wholistic-analytic cognitive styles, search task type, and experience variables in using the Web. Method: This study is an applied research using survey method. A total of 321 search queries were submitted by 44 users. Data collection tools were Riding’s Cognitive Style A...

متن کامل

Exploring Neural Correlates of Different Dimensions in Drug Craving Self-Reports among Heroin Dependents

Introduction: Drug craving could be described as a motivational state which drives drug dependents towards drug seeking and use. Different types of self-reports such as craving feeling, desire and intention, wanting and need, imagery of use, and negative affect have been attributed to this motivational state. By using subjective self-reports for different correlates of drug craving along ...

متن کامل

I-34: Interactorme of Human Embryo Implan Implantation:Pathways,Networks

Background: A prerequisite for successful embryo implantation is adequate preparation of receptive endometrium and the establishment and maintenance of a viable embryo. The success of implantation further relies upon a two-way dialogue between the embryo and uterus. However, molecular bases of these preimplantation and implantation processes in humans are not well known. Materials and Methods: ...

متن کامل

Exploring the Role of Cognitive and Procedural Task Complexity in EFL Learners' Attention to L2 System and Form-focused Self-repairs

In L2 development, the cognitive complexity of tasks plays a crucial role in task performance and language features produced. However, there have only been few studies addressing the impact of task complexity on EFL learners' attention to L2 system and form-focused self-repairs (FFS).This study explores the role of increasing cognitive task complexity in EFL learners' form-focused attention (FF...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2011